Revia is a white, crystalline compound. The hydrochloride salt is soluble in water to the extent of about 100 mg/mL. Revia is available in scored film-coated tablets containing 50 mg of naltrexone hydrochloride.
Revia Tablets also contain: colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, red iron oxide, yellow iron oxide and titanium dioxide.
Take this medication by mouth with or without food, usually 50 milligrams once daily or as directed by your doctor. This medication may be given as part of a program where a health care professional will watch you take the medication. In this case, your doctor may order a higher dose (100-150 milligrams) to be taken every 2-3 days to make it easier to schedule clinic visits. Naltrexone may be taken with food or antacids if stomach upset occurs. A urine test should be done to check for recent opiate drug use. Your doctor may give you another medication (naloxone challenge test) to check for opiate use. Do not use any opiates for at least 7 days before starting naltrexone. You may need to stop certain opiate drugs (such as methadone) 10 to 14 days before starting naltrexone. Dosage is based on your medical condition and response to treatment. Your doctor may start you at a lower dose and monitor you for any side effects or withdrawal symptoms before increasing your dose. Take this medication as directed. Do not increase your dose, take it more often, or stop taking it without your doctor’s approval.
The dosage of this product is dictated by the kind of dependence and whether there will be supervision of the medication or not. To treat addiction to alcohol, the recommended Revia dose is 50 mg once a day. To treat dependence on opioid such as heroin or methadone, the dose will vary significantly but will start at 25 mg daily which can be increased daily at a slow pace until the right amount of dose is achieved. Your physician will prescribe the most appropriate dosage based on your individual condition and it’s important that you take the medication as it has been prescribed by the doctor. But before putting you on this treatment, the doctor may ask you to do a urine sample test just to make sure that you haven’t use heroine, methadone and a variety of other opioid drugs within the past 10 days. You shouldn’t take this Revia if you have used these drugs within that period of time. The doctor may ask for a NARCAN test review or challenge just to make sure that there is no opioids in your body before recommending Revia for the treatment of the dependence.
Nausea, headache, dizziness, anxiety, tiredness, and trouble sleeping may occur. In a small number of people, mild opiate withdrawal symptoms may occur, including abdominal cramps, restlessness, bone/joint pain, muscle aches, and runny nose. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Sudden opiate withdrawal symptoms can occur within minutes after taking naltrexone. Tell your doctor right away if any of these withdrawal symptoms occur: abdominal cramps, nausea/vomiting, diarrhea, joint/bone/muscle aches, mental/mood changes (e.g., anxiety, confusion, extreme sleepiness, visual hallucinations), runny nose.
Before taking Revia, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current or recent use (in the last 7 to 14 days) of any type of opioid drug (such as morphine, methadone, buprenorphine), kidney disease, liver disease. You should carry or wear medical identification stating that you are taking this drug so that appropriate treatment can be given in a medical emergency.
Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Some products that may interact with this drug include: cough medication (e.g., dextromethorphan), disulfiram, diarrhea medication (e.g., diphenoxylate), narcotic medication (e.g., codeine, hydrocodone, propoxyphene), thioridazine. This medication may interfere with certain laboratory tests (including drug tests), possibly causing false test results.