You should not use this medicine if you are allergic to Plavix, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury). Some medicines can interact with Plavix and should not be used at the same time. Your doctor may need to change your treatment plan if you also take other medicines, especially certain stomach acid reducers (esomeprazole, omeprazole, Nexium, Prilosec). To make sure Plavix is safe for you, tell your doctor if you have: a bleeding or blood clotting disorder, such as TTP (thrombocytopenic purpura) or hemophilia; a history of stroke, including TIA (“mini-stroke”); a stomach ulcer or ulcerative colitis; kidney disease; or if you are allergic to medicines like clopidogrel, such as prasugrel, ticagrelor, or ticlopidine. This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether clopidogrel passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Most people take Plavix once a day. It’s a good idea to take this drug with food and lots of water in order to reduce the side effects. Never stop taking Plavix without talking to your doctor. Most people with unstable angina or heart attack begin with a 300-mg dose, followed by 75 mg once a day, taken together with 75 to 325 mg of aspirin. If you have peripheral arterial disease or have had a recent stroke, your doctor will likely prescribe a dose of 75 mg daily.
Common side effects of Plavix include: Itching Eczema Rash Head or joint pain Bruising Diarrhea Fever Skin redness Taste problems Stop taking Plavix and contact your doctor if you experience any of the following serious side effects: Nosebleed Bloody or tarry stools Blood in your urine Coughing up blood Vomiting that looks like coffee grounds Crushing heavy chest pain that spreads to arm, shoulder, or jaw Sudden numbness or weakness, especially on one side of your body Sudden headache Confusion Vision, speech, or balance problems Weakness Fever Pale skin or yellowing of the skin or eyes (jaundice) Purple or red pinpoint spots under your skin Unusual bleeding in the mouth, vagina, or rectum Get emergency help if you exhibit the following signs of an allergic reaction to Plavix: Hives Difficulty breathing Swelling of the face, lips, tongue, or throat