Plavix (Generic)

Plavix (Generic)


Plavix is effectively used to treat and prevent heart attack, stroke, blood clots, and acute coronary syndrome. Plavix is a registred trademark of Sanofi-Aventis.
Plavix is the brand name form of the generic drug clopidogrel bisulfate, an anti-platelet medication that’s used to prevent blood clots.
 Blood clots can form in blood as a result of certain heart or blood vessel conditions.
 For example, Plavix is often prescribed following a heart attack or stroke.
 Plavix is also given to those who have unstable angina or peripheral artery disease.
 Using Plavix in combination with aspirin may be more effective in preventing another heart attack, but this will increase your risk of bleeding.
 Marketed by Bristol-Myers Squibb and Sanofi, Plavix was initially approved by the Food and Drug Administration (FDA) in 1997.

You should not use this medicine if you are allergic to Plavix, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury). Some medicines can interact with Plavix and should not be used at the same time. Your doctor may need to change your treatment plan if you also take other medicines, especially certain stomach acid reducers (esomeprazole, omeprazole, Nexium, Prilosec). To make sure Plavix is safe for you, tell your doctor if you have: a bleeding or blood clotting disorder, such as TTP (thrombocytopenic purpura) or hemophilia; a history of stroke, including TIA (“mini-stroke”); a stomach ulcer or ulcerative colitis; kidney disease; or if you are allergic to medicines like clopidogrel, such as prasugrel, ticagrelor, or ticlopidine. This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether clopidogrel passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Most people take Plavix once a day. It’s a good idea to take this drug with food and lots of water in order to reduce the side effects. Never stop taking Plavix without talking to your doctor. Most people with unstable angina or heart attack begin with a 300-mg dose, followed by 75 mg once a day, taken together with 75 to 325 mg of aspirin. If you have peripheral arterial disease or have had a recent stroke, your doctor will likely prescribe a dose of 75 mg daily.

Common side effects of Plavix include: Itching Eczema Rash Head or joint pain Bruising Diarrhea Fever Skin redness Taste problems Stop taking Plavix and contact your doctor if you experience any of the following serious side effects: Nosebleed Bloody or tarry stools Blood in your urine Coughing up blood Vomiting that looks like coffee grounds Crushing heavy chest pain that spreads to arm, shoulder, or jaw Sudden numbness or weakness, especially on one side of your body Sudden headache Confusion Vision, speech, or balance problems Weakness Fever Pale skin or yellowing of the skin or eyes (jaundice) Purple or red pinpoint spots under your skin Unusual bleeding in the mouth, vagina, or rectum Get emergency help if you exhibit the following signs of an allergic reaction to Plavix: Hives Difficulty breathing Swelling of the face, lips, tongue, or throat

Do not miss doses Always follow the prescription, use a reminder if you have to. This is because skipping a dose can be harmful and will disorganize your treatment plan. If you miss a dose, always take it immediately you realize that. If it is already time to take another dose, just let go the one you missed and continue taking the tablets as advised. Never take two doses of Plavix at once. Never take Plavix over the counter Always do this under a doctor’s advice. It is important that you undergo the required tests to ascertain that you are in good condition for the drug. Things such as allergies, enzyme activity, genetic factors, and medical history should be put into consideration.
Before beginning Plavix, it’s important that you provide your doctor with a complete list of all the prescription and non-prescription drugs you’re taking, including vitamins and herbal products, since they could interact with Plavix. For example, combining Plavix with the following drugs could increase your risk of stomach and/or intestinal bleeding: Ibuprofen (Motrin, Advil, Nuprin) Naproxen (Naprosyn or Aleve) Etodolac (Lodine) Celecoxib (Celebrex) Diclofenac (Cataflam or Voltaren) Indomethacin (Indocin) Meloxicam (Mobic) There are many other NSAIDs that can raise the risk of similar bleeding problems. In 2009, the FDA warned against combining Plavix with acid-reducing products like esomeprazole (Nexium) or omeprazole (Prilosec) since they could substantially reduce the medication’s effectiveness because they inhibit the enzyme CYP 2C19, which activates Plavix. These products are designed to reduce acid in your stomach. Other medications that inhibit this enzyme include: Cimetidine (Tagamet) Fluoxetine (Prozac, Sarafem, and Symbyax) Fluvoxamine (Luvox) Ticlopidine (Ticlid) Fluconazole (Diflucan) Ketoconazole (Nizoral) Voriconazole (Vfend) Etravirine (Intelence) Felbamate (Felbatol) In addition to avoiding medications or products that interact with Plavix, it’s important to stay away from activities that could lead to bleeding or injury. You should also be careful about triggering bleeding when you shave or brush your teeth. Try not to drink alcohol since it could also increase the risk of stomach or intestinal bleeding.