Norvasc

Norvasc

$150,00

Norvasc is also used to treat coronary artery disease (CAD) in patients without heart failure, and certain types of angina (chest pain) from CAD, such as activity- and stress-induced angina (chronic stable angina), and angina that occurs at rest (Prinzmetal’s angina).
Taken regularly, Norvasc can control angina, but it doesn’t stop chest pain after it has already begun.
The drug can also lower a person’s risk of cardiovascular events related to high blood pressure, such as strokes and heart attacks.
Norvasc belongs to a class of drugs called calcium channel blockers, which block the flow of calcium into heart muscles and the muscles along the walls of blood vessels.
Because the contraction of these muscles depends on calcium, Norvasc relaxes and widens blood vessels, thereby improving blood flow.
Doctors also sometimes prescribe Norvasc “off-label” for the treatment of cluster headaches, migraines, Raynaud’s syndrome (a blood vessel disorder), and congestive heart failure.
Manufactured by Pfizer, Norvasc was first approved by the Food and Drug Administration (FDA) in 1987.
In the early 1990s, researchers conducted the so-called PRAISE study, which was backed by Pfizer, to determine if Norvasc could help reduce the risk of death in people with severe heart failure.
Though the study found little overall benefits to severe heart failure patients, it suggested that Norvasc might prolong the life of a subgroup of people with heart failure from non-ischemic cardiomyopathy (cardiac muscle damage not associated with low blood supply to the coronary arteries).
To investigate this possibility, Pfizer-sponsored the PRAISE-2 study, which found no benefit to the subgroup in the PRAISE-1 trial and was presented at a conference in 2000.
However, results of the study weren’t published in an academic journal until 2013, leading some experts to question whether Pfizer intentionally delayed publication to prevent the data and findings from being publicly available.

Lisinopril is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to improve survival after a heart attack. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to help protect the kidneys from harm due to diabetes.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are using the suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. The dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take 2 to 4 weeks before you get the full benefit of this medication. For the treatment of heart failure, it may take weeks to months before you get the full benefit of this medication. Tell your doctor if your condition does not improve or if it worsens (such as your blood pressure readings remain high or increase).

Dizziness, lightheadedness, tiredness, or headache may occur as your body adjusts to the medication. Dry cough may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat), change in the amount of urine. This drug may rarely cause serious (possibly fatal) liver problems. Tell your doctor right away if you notice any of the following rare but serious side effects: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Before taking lisinopril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (such as benazepril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), high level of potassium in the blood. This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Too much sweating, diarrhea, or vomiting may cause loss of too much body water (dehydration) and increase your risk of lightheadedness. Report prolonged diarrhea or vomiting to your doctor. Be sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Older adults may be more sensitive to the side effects of this drug, including dizziness and increases in potassium level. This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details. (See also Warning section.) It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Some products that may interact with this drug include: aliskiren, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone). Check the labels on all your medicines (such as cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure or worsen your heart failure. Ask your pharmacist for more details. A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking lisinopril. Make sure all your doctors know which medicines you are using.