Glucophage Metformin belongs to the class of medications called oral hypoglycemics, which are medications that lower blood sugar. It is used to control blood glucose (blood sugar) for people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been found to lower blood glucose well enough on their own.
Metformin works by reducing the amount of glucose made by the liver and by making it easier for glucose to enter into the tissues of the body. Metformin has been found to be especially useful in delaying problems associated with diabetes for overweight people with diabetes.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this Glucophage Metformin come in?
Glucophage Metformin 500 mg
Each white, round, biconvex tablet, scored on one side and debossed with “HMR” on the other, contains metformin HCl 500 mg. Nonmedicinal ingredients: magnesium stearate and povidone.
Glucophage Metformin 850 mg
Each white, oblong tablet, debossed with “HMR” on one side and “850” on the other, contains metformin 850 mg. Nonmedicinal ingredients: magnesium stearate and povidone.
Each white, oval, biconvex, film-coated tablet, with a line on both sides and “1000” engraved on one side, contains metformin HCl 1000 mg. Nonmedicinal ingredients: magnesium stearate and povidone. Tablet coating: hypromellose and macrogol.
How should I use this medication?
The recommended adult dose of metformin ranges from 500 mg 3 or 4 times a day to 850 mg 2 or 3 times a day or 1000 mg 2 times a day. The maximum daily dose should not exceed 2,550 mg daily. Tablets should be taken with food whenever possible to reduce the risk of nausea and vomiting. Metformin may be used alone or with other medications that reduce blood sugar. To ensure that the medication is working well, monitor your blood glucose on a regular basis as directed by your doctor or diabetes educator.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to metformin or any ingredients of this medication
- are experiencing or recovering from severe infections, trauma, or surgery
- are pregnant or breast-feeding
- are suffering severe dehydration (have lost a lot of water from your body)
- are undergoing radiologic studies involving use of iodinated contrast materials
- drink large amounts of alcohol in the short term or on a regular basis
- have a history of lactic acidosis or acute/chronic metabolic acidosis (too much acid in the blood), diabetic ketoacidosis with or without coma, or history of ketoacidosis with or without coma
- have diseases associated with lack of oxygen to the tissues such as cardio-respiratory insufficiency
- have reduced kidney function
- have severe liver disease
- have type 1 diabetes (people with type 1 diabetes should always be using insulin)
- have very poor blood glucose control (these people should not take this medication as the only antidiabetic agent)